Description
Bactrim DS Tablet – Sulfamethoxazole 800 mg / Trimethoprim 160 mg
Bactrim DS is a prescription antibiotic combining sulfamethoxazole and trimethoprim, commonly used to treat various bacterial infections. The “DS” stands for “double strength,” indicating the higher dosage compared to standard formulations.
Uses
Bactrim DS is prescribed for:
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Urinary tract infections (UTIs)
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Respiratory infections (e.g., bronchitis, pneumonia)
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Middle ear infections (otitis media)
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Traveler’s diarrhea
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Shigellosis (intestinal infection)
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Toxoplasmosis
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Pneumocystis jirovecii pneumonia (PCP), especially in immunocompromised patients
How It Works
Sulfamethoxazole inhibits bacterial folic acid synthesis, while trimethoprim blocks a subsequent step in the pathway.Together, they disrupt bacterial DNA synthesis, effectively killing or inhibiting bacterial growth.
Dosage
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Adults: 1 Bactrim DS tablet (800 mg sulfamethoxazole / 160 mg trimethoprim) every 12 hours for 10–14 days, depending on the infection type.
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Children (12 years and older): Dosage based on weight, typically 1 tablet every 12 hours.
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Renal Impairment: Dosage adjustments are necessary for patients with impaired kidney function.
Precautions
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Allergies: Avoid if allergic to sulfa drugs or trimethoprim.
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Liver/Kidney Issues: Use with caution; dosage adjustments may be needed.
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Pregnancy/Breastfeeding: Not recommended during pregnancy; consult a doctor if breastfeeding.
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Children: Not recommended for infants under 2 months.
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Hydration: Maintain adequate fluid intake to prevent crystalluria (cloudy urine).
Side Effects
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Common: Nausea, vomiting, rash, loss of appetite.
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Serious: Severe allergic reactions, liver damage, blood disorders, kidney problems.
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Photosensitivity: Increased sensitivity to sunlight; use sunscreen and protective clothing.
Additional Information
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Alcohol: Avoid alcohol during treatment to prevent side effects like nausea and flushing.
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Drug Interactions: Inform your doctor about all medications, including over-the-counter drugs and supplements, as Bactrim DS can interact with various medications.
